C1q Antikörper
Kurzübersicht für C1q Antikörper (ABIN639406)
Target
Alle C1q Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse Anti-Human C1q
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Spezifität
- DS-MB-02778 recognizes human complement component 1, q subcomponent (C1q), a 156kDa secreted protein. C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.
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Produktmerkmale
- Blood Coagulation Proteins
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Aufreinigung
- Purified
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Immunogen
- Binds globular head domain of C1q, purified from human plasma.
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Isotyp
- IgG1
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Applikationshinweise
- Immunohistology - Frozen, ELISA (dilution: 1:500, 1:1000), Flow Cytometry, Immunofluorescence
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/ml
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Buffer
- Borate buffered saline, pH 8.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- C1q (Complement Fragment C1q (C1q))
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Andere Bezeichnung
- C1q
Target
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